Search results for "Physician's Role"

Immunoaffinity purification and characterization of mitochondrial membrane-bound D-3-hydroxybutyrate dehydrogenase from Jaculus orientalis.

2008

Abstract Background The interconversion of two important energy metabolites, 3-hydroxybutyrate and acetoacetate (the major ketone bodies), is catalyzed by D-3-hydroxybutyrate dehydrogenase (BDH1: EC 1.1.1.30), a NAD+-dependent enzyme. The eukaryotic enzyme is bound to the mitochondrial inner membrane and harbors a unique lecithin-dependent activity. Here, we report an advanced purification method of the mammalian BDH applied to the liver enzyme from jerboa (Jaculus orientalis), a hibernating rodent adapted to extreme diet and environmental conditions. Results Purifying BDH from jerboa liver overcomes its low specific activity in mitochondria for further biochemical characterization of the e…

Prognostic factors and predictors of outcome in children with autism spectrum disorder: the role of the paediatrician.

2021

Abstract Background Autism spectrum disorder is a complex condition with wide variation in type and severity that involves persistent challenges in social interaction, speech and nonverbal communication, restricted/repetitive behaviours and adaptive behaviours. In recent years, research has deepened the study of the predictive factors of optimal outcome, intended as indicators of positive trajectory in children with a previous diagnosis of autism who, after a therapeutic path, show a significant reduction in the “core” symptoms of autism and a positive evolution in social, adaptive, affective, and relational skills. Methods The study included 40 children aged 21 to 66 months, enrolled betwe…

Physician specialty as a source of heterogeneity in the care of patients with COPD.

2011

Clinical presentation of patients with suspected obstructive sleep apnea and self-reported physician-diagnosed asthma in the ESADA cohort.

2018

Obstructive sleep apnea (OSA) and asthma are often associated and several studies suggest a bidirectional relationship between asthma and OSA. This study analyzed the characteristics of patients with suspected OSA from the European Sleep Apnea Database according to presence/absence of physician-diagnosed asthma. Cross-sectional data in 16,236 patients (29.1% female) referred for suspected OSA were analyzed according to occurrence of physician-diagnosed asthma for anthropometrics, OSA severity and sleepiness. Sleep structure was assessed in patients studied by polysomnography (i.e. 48% of the sample). The prevalence of physician-diagnosed asthma in the entire cohort was 4.8% (7.9% in women, …

Influence of the Geriatric Oncology Consultation On the Final Therapeutic Decision In Elderly Subjects With Cancer: Analysis of 191 Patients

2014

International audience; Objectives: evaluate the impact of the Geriatric Oncology consultation on the final therapeutic management of cancer in elderly patients aged 70 and older. Design: retrospective study. Setting: the Pilot coordination unit in Geriatric Oncology of Cote d'Or, Burgundy, France. Participants: From January 2010 to December 2010, 191 patients with cancer aged 70 and older. Measurements: the concordance between the treatments proposed following the tumor Board, those proposed following the Geriatric evaluation (GE) and those actually given to the patients was evaluated using the kappa agreement test. Results: One hundred and ninety-one patients were included. Mean age was 8…

Impact of Distressing Media Imagery on Children

2016

Children are particularly fragile and vulnerable to the impact of traumatic events or their mediated representation because they lack the skills and experience in the management of difficult information. Children have different concepts of health and disaster than adults and institutions, depending mainly on their cognitive, emotional, social, psychological, and physical development. If left alone with threatening messages, children are less able to fully understand the information to which they had been exposed. Therefore, they may fail to integrate the external data into their psychological schema of coping strategies. Children usually count on caregivers to deal with stressors, and they …

The governments' doctors: the roles and responsibilities of chief medical officers in the European Union.

2010

The regular meetings of the chief medical officers (CMOs) from the European Union's (EU's) 27 Member States provide an important forum to address issues of common interest affecting Europe's populations. Yet there is no universally agreed role for a CMO. This article describes the findings of a study, based on interviews with key informants and documentary analysis that sought to describe their diverse roles. For the purpose of this article, CMOs are defined as those sent by their governments to the regular EU meetings of CMOs. Four broad categories of countries were identified: those whose CMO is the most senior doctor in the health ministry, in some cases with responsibility spanning all …

From Nazi holocaust to nuclear holocaust: a lesson to learn?

1986

In a 1986 address to the International Physicians for the Prevention of Nuclear War, a German physician describes his profession's embrace of National Socialism. The nationalistic sentiments of German scientists led them to identify with the goals of the Third Reich and to participate in its programs. He gives examples of physician involvement in the Nazi Party, discrimination against "non-Aryan" doctors, "eugenic" mass murder, and lethal experiments with human subjects. The few who protested were regarded as traitors by the profession as a whole, and post-war apologists argue that physicians' organizations had no choice but to collaborate with the Nazis. Hanauske-Abel rejects this reasonin…

The Role of Pediatricians in Caring for the Well-Being of Children Living in New Types of Families.

2017

Pediatricians are on the front line of child care and advocacy, and it is their role to promote children's well-being and to help parents raise healthy children, independent of the configuration of their families. This report aims to draw attention to the evolving social scenarios and to emphasize that pediatricians must be trained to coordinate new challenges that may arise from differently configured families, particularly single-parent and same-sex–parent families.

Handling and pathology reporting of specimens with carcinoma of the urinary bladder, ureter, and renal pelvis.

2003

Abstract Objective: Pathologists play a pivotal role in the diagnosis and in the report of the pathological features related to prognosis. Methods: To meet these endpoints, the following issues must be accomplished: adequate information about the patient history, proper handling of the specimens, identification of the reliable histopathological techniques necessary to reach the more detailed diagnostic information and evaluate the prognostic variables, and a standardized pathological report. Results: Recent efforts to standardize the histopathological evaluation have generated significant confusion among the urological and pathological communities as well. No consensus has been achieved abo…